Atorvastatin belongs to a group of medicines called statins.

It's used to lower cholesterol if you've been diagnosed with high blood cholesterol. It's also taken to prevent heart disease, including heart attacks and strokes. Your doctor may prescribe atorvastatin if you have a family history of heart disease, or a long-term health condition such as type 1 or type 2 diabetes or rheumatoid arthritis.

This medicine is available on prescription only. It comes as tablets, including chewable tablets for people who have difficulty swallowing.

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Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses. Regulators and risk managers in general need to decide whether an allergenic food or ingredient is of such public health importance that it needs to be actively managed. Tissue-engineered tracheal transplants may offer a treatment strategy to address advanced structural disorders of the large airway.

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We hypothesized that the cellular transduction rate (and thus overall efficiency) would be improved by agents that could maintain a prolonged, high pericellular vector concentration. Glufosinate-tolerant crops have been commercialized using one of these two transgenes. Subsequently, the cat developed anterior uveitis refractory to topical therapy that eventually necessitated enucleation. We conducted a case-control study in a Chinese Han population including 360 EC cases and 310 controls to evaluate whether these variants are related to EC susceptibility. A flow-cytometric assay based on Annexin V/ propidium iodide (Annexin V/PI) was used to measure the PS exposure of erythrocytes.

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We examined the frequency of dissociative seizures in inpatients of a specialized ward for epilepsy as well as their diagnostic and therapeutic course. To better understand the nature of the forces condensing protamine-DNA assemblies and their dependence on amino acid content, the effect of neutral and negatively charged amino acids on DNA-DNA intermolecular forces was studied using model peptides containing six arginines.

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A model was devised to account for the sequences found in various dicot tree species. A systematic review of the effectiveness of therapeutic interventions on quality of life (QoL) for adult vitiligo patients.

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The emp protein, as predicted from the nucleotide sequence, is 519 amino acid residues long. This approach focuses on movement patterns rather than isolated muscle exercises.

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Many factors are taken into account for selecting carrier type and encapsulation method. The effectiveness of psychosocial interventions for family caregivers on the psychosocial wellbeing, physical health and quality of life of stroke family caregivers and their stroke survivors: a systematic review. Apaf1 plays a pro-survival role by regulating centrosome morphology and function. In addition, we report on anomalous resonance effects in the low-frequency region of the WS2 Raman spectrum. Programmed Death-Ligand 1 Expression in Muscle-Invasive Bladder Cancer Cystectomy Specimens and Lymph Node Metastasis: A Reliable Treatment Selection Biomarker?

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Immunoblotting with phosphotyrosine antibodies revealed that tyrosine phosphorylation of alpha-tubulin in PC12 cells occurred within 10 min of nerve growth factor (NGF) treatment. Its use in hyperthyroidism has increased in the UK since we last reviewed this subject (e.g. Particular emphasis was given to short- and long-term outcomes in relation to AEF repair type. To describe the demographics, characteristics, management pitfalls, and outcomes of pseudoptosis associated with congenital fibrosis of the extraocular muscles (CFEOM). Sulphonic acid strong cation-exchange restricted access columns in sample cleanup for profiling of endogenous peptides in multidimensional liquid chromatography.

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The final identity and functional properties of a neuron are specified by terminal differentiation genes, which are controlled by specific motifs in compact regulatory regions. Evidence from recent studies indicates that prostate carcinogenesis depends on the altered expression of several factors including androgen receptor signaling, proinflammatory, and cell cycle regulatory genes. Samples from 908 patients with suspected CTD seen in rheumatology clinics were collected prospectively at 3 tertiary care centers.

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We have constructed recombinant retroviral vectors carrying the cDNA encoding human FAH. Descriptive analysis was used to illustrate findings regarding the trends of the BPS model in medical education and its utility in specific medical schools in the United States. PTSD, depression, and CM exposure were assessed via structured interviews.

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A series of experiments, using the default pipetting parameters, was performed which demonstrated that the difference in the reported volume was due to a dilution effect by the system liquid of the liquid handler and did not indicate an error in the delivered volumes. These observations confirm a proposed model for the structure of the erupting periodontal ligament and suggest that the method used will provide further information about the role of the ligament in tooth support and eruption. Three certified athletic trainers classified the knee posture of each subject during the OHS on two different occasions using screening guidelines.

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Metabolic control in patients with schizophrenia treated with amisulpride or olanzapine. Introduction of blended learning in a master program: Developing an integrative mixed method evaluation framework. An emerging consensus on recommendations to facilitate clinical gene transfer. The photocatalytic degradation kinetics of methylene blue fitted a potential model with n orders ranging from 0.5 to 6.9.

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Cases were identified with good sensitivity, specificity and positive predictive value with SDO data, with better rates than similar previously published algorithms based on Italian data. Quality of life research in head and neck cancer: a review of the current state of the science. Culture historical data on the anatomical illustrations of Leonardo da Vinci Osteoporosis is a common condition, especially affecting the older female population. Participants also found that there were actual mistakes in their health data reports.

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The cause of these high levels can be residual thyroid tissue, possibly with C-cell hyperplasia, and/or residual micro-MTC foci. Disaggregation with 6 M urea, autoclaving, and alkaline solution was incomplete, and injection of these AApoAII fibrils induced mild amyloidosis. The location and concentration of ETA and ETB receptors were studied by means of immunohistochemistry together with confocal microscopy after overnight incubation with selective antibodies. These results indicate that proline-rich stretches attenuate the potential of stem cell active homeobox genes to acquire oncogenic properties. Success in deep biliary cannulation via native ampullae of Vater is an accepted measure of competence in ERCP training and practice, yet prior studies focused on predicting adverse events alone, rather than success.

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Many of these genes are in or near LTR (long-terminal repeat) retrotransposons. These bacteria may be used as stable bioindicators to measure perturbation of the metabolic state by physical and chemical agents.

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Guidelines for submission are available at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1741-6787. Activated charcoal should be given if less than two hours have passed since paracetamol intake. Age influences the risk of recurrence, and age and comorbidities significantly influence the risk of death without recurrence. Collectively, the results of this study appear to suggest that YlaC regulated by the YlaD redox state, contribute to oxidative stress resistance in B.

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So far, few data are available about biologic markers, who may predict the individual risk for developing depressive symptoms during IFN-alpha therapy. This is the first report concerning the use of abciximab in primary stenting for acute myocardial infarction in allograft coronary artery disease. Identification of novel single nucleotide polymorphisms (SNPs) of the lipoprotein lipase (LPL) gene associated with fatty acid composition in Korean cattle. These effects on multiple genes controlling both apoptosis and proliferation are in line with the functional effects of LUCA-15/RBM5 and indicate that it plays a central role in regulating cell fate consistent with its tumor suppressor activity.

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Overview of Actual Findings and Design of the Epidemiological DIARET SK Study The aim of this review is to report all current data about the IGF system involvement in GIST, focusing on the current clinical implication and future perspectives. In addition, we observed a novel role for a subset of splicing components in lin-35 Rb-controlled processes. There are a number of architectural requirements such as image receive (from multiple field sites), a database for storing quantitative measures, and data mining and reporting capabilities.

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Regions with higher Medicare Part D spending show better drug adherence, but not lower medicare costs for two diseases. In a scenario of protein families or functionally related (or even dissimilar) sets this leads to a more difficult task of using annotations to compare the extent of functional relatedness among all family or set members. Clinical outcome of WS patients may thus be improved by counselling them regarding smoking cessation or other exposure and by proposing antifibrotic therapy. Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation.

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The endopelvic component had a liquid-density varying between 15 and 30 HU, with contrast enhancement of its wall and internal septations. Increases of cfDNA are described to be a potential hallmark for the overtraining syndrome, and might be related to aseptic vascular inflammation in athletes. Exploring the genome of this organism will facilitate the understanding and isolation of the gene(s) involved in its extreme osmotolerance. We propose that this intercellular communication pathway may serve as a sensor mechanism for infiltrating B cells to recognize an appropriate environment to initiate reactivation, thereby allowing the exchange of virus to the oral epithelium. However, recent progress in atmospheric plasmas has led to the creation of cold plasmas with ion temperature close to room temperature.

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Tissue specimens were taken from 38 patients with primary hyperparathyroidism (HPT) (17 adenomas and 21 primary hyperplasias) and from 30 patients with secondary HPT. Shortly after this, she had an unsuccessful pregnancy which resulted in a spontaneous abortion at 6/7 weeks.

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In vitro phosphorylation and kinase assays in Neurospora crassa. Estimates of GFR based solely on serum cystatin C levels had the same predictive potential when compared with the MDRD-4 and C-G formulas. All patients had documented exposure to gadolinium-based contrast agents.

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CNT stacks are fabricated by water-assisted selective etching and the cyclic introduction of ethylene into the chemical vapor deposition (CVD) reactor. Improvements in user-friendly data management together with a more powerful interpretation of results should increase the use of field HTPPs, therefore increasing the efficiency of crop genetic improvement to meet the needs of future generations. However, studies of long-term outcomes regarding tumor recurrence and patient survival in comparison with the conventional open approach are limited. To report results in patients undergoing lower eyelid reconstruction following Mohs surgery using a combination of surgical techniques, the rhomboid skin flap and a sliding tarsal flap.

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Furthermore, they support the hypothesis that immature or impaired production of allergen-specific IgA2 may be associated with the pathophysiology of food allergy, a defect that seems to be selective for the culprit allergen. Distant histochemical changes in cells of the central nervous system after the administration of the ganglionic-blocking agents gangleron The DO concentration in the first aerobic zone, when receiving constant aeration, and the net pH change between the last and first aerobic zones display strong correlations with the influent ammonia concentration for the domestic wastewater used in this study.

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Signaling through a G Protein-coupled receptor and its corresponding G protein follows a stoichiometrically limited model. Hexavalent chromium Cr(VI), a highly toxic oxyanion, widely occurs in drinking water supplies. It appears that the PDI-21 is a useful instrument to measure dimensionality of delusional ideation in Spanish general population. Molecular diversity of voltage-gated sodium channel alpha and beta subunit mRNAs in human tissues.

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Nitrogen retention capacity was exceeded on one site, leading to nitrate leaching and extremely low pH. This heterogeneity may contribute to the fine-tuning of signal amplitudes and duration from different receptors. For most of the past half century, medical approaches for treating cancer have relied primarily on cytotoxic chemotherapeutics that interfere with DNA replication and cell division, susceptibilities of rapidly dividing cancer cells. Moreover, a preventive effect on MTXinduced toxicity is a novel finding of S. Microdialysis in clinical practice: monitoring intraoral free flaps.

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Influence of pH, heat, deoxycholate and ether on arbovirus haemoagglutinin. An inhibitor of the membrane attack complex of complement was isolated from the membranes of sheep erythrocytes. To describe the clinical features of a novel variant of autosomal recessive lower motor neuron disease (LMND) with childhood onset and to map the disease-causing gene.

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Infections are the leading cause of morbidity and mortality after colorectal surgery. We also used real-time RT-PCR to examine the expression of molecules associated with EMT before and after chemoradiotherapy. Fifty-three patients with suspected pulmonary embolism had lung scans using the SPECT technique as well as 16-slice multidetector-row spiral CT within an interval of 48 h. Ratios of contents of selected representatives of each group to the sum of all identified markers were proposed as definite parameters for determination of roasting degree of Brazilian coffee Arabica.

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We believe that these strategies will improve patient understanding of CVD risk, identify new sections of the population who might benefit from preventive therapy, and motivate lifestyle changes and adherence to therapy early in the course of disease progression. Interim analysis: A rational approach of decision making in clinical trial. Coronary stent assessability by 64 slice multi-detector computed tomography. Ovarian dysgerminoma is the most common ovarian malignancy in young women.

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We report here that blood neutrophils (PMN) of patients with the sepsis syndrome (sepsis PMN) are consistently tolerant to endotoxin-induced expression of the IL-1 beta gene, as determined by decreased synthesis of the IL-1 beta protein and reductions in IL-1 beta mRNA. This multi-system, polygenic, multi-factorial disorder is associated with an increased risk for metabolic abnormalities such as type 2 diabetes mellitus. The present work extended the current knowledge about the cardioprotective benefits from the adoption of the Mediterranean diet by showing an additional protective effect on ischemic stroke development.

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The median time of survival for the group with poor expression of ICAM-1 was 51 months and only 9 months for the group with strong expresssion. Propionibacterium acnes in shoulder surgery: is loss of hair protective for infection? Clinical studies on the EEG-activating effects of Na-beta, beta-pentamethylene-gamma-hydroxybutyrate, a new central stimulant.

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As a result, we were able to quantify the surface and deep muscle activity by measuring the muscle thickness, pennation angle and long-axis displacement, from the ultrasound images. Test preparation and seeking research experience during undergraduate medical education may be effective approaches for increasing the likelihood of success for US seniors matching into a surgical specialty. Academics are from Mars, humanitarians are from Venus: Finding common ground to improve research during humanitarian emergencies.

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Clinical trials of repeated injection of replacement enzyme into CSF are underway in patients with the inherited neurodegenerative disorder mucopolysaccharidosis type IIIA. Even though the Poly(l-histidine) (PHis) based copolymers have been well studied, the effect of the chemically substituted l-histidine on the physio-chemical and biological properties of the micelles has never been elucidated to date.

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The type B pattern is characterized by a generalized absence of subcutaneous tissues. as additional vectors with potential importance in malaria transmission after the wet season. An Arden Syntax knowledge base consists of rules called Medical Logic Modules (MLMs), which are stored as simple ASCII files that can be written on any text editor.