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Aviral (Acyclovir)

Aviral is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Aviral is converted to an active form by the virus itself, and the virus then uses the active form of Aviral rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Aviral into new viral DNA stops the production of the DNA. Virally infected cells absorb more Aviral than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Aviral in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Viroclear, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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This medication is used in certain people to treat outbreaks of herpes simplex infection of the skin (e. g. , genitals), mucous membrane areas (e. g. , mouth, nose), or brain. It is also used in certain people to treat shingles infection. The viruses that cause these infections live in the body quietly until an outbreak occurs. Aviral does not cure these infections, but can speed healing of the sores, decrease pain/itching/formation of new sores, and lower the risk of other problems from the virus (e. g. , infection spreading to other parts of the body/organs, persistent pain after sores heal).

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Moreover, Ben/dUev1a could cooperate with Ras(V12) to promote tumor overgrowth and invasion. Prevention of anaphylactic shock caused by intravenous iodine in radiology.

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One of the most urgent vascular circumstances: Acute limb ischemia. Dissection was directed to the bilaminar posterior layer of the thoracolumbar fascia of 10 human specimens. Site-directed mutagenesis experiments showed that the rtS117F mutation by itself did not confer lamivudine resistance but it compensated for replication deficiency of the rtM204I mutant in HepG2 and Mahlavu cells. Higher dosing should be considered in such patients, although in case of renal impairment and reduced clearance, drug accumulation could also result in some side-effects.

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This study examined the effect of the smear layer on the antibacterial effect of different disinfecting solutions in infected dentinal tubules. Effects of maternal prenatal smoking and birth outcomes extending into the normal range on academic performance in fourth grade in North Carolina, USA. In this study, the effects of overlapping fast and slow waves on measurements of the apparent attenuation as a function of propagation distance are investigated along with methods of analysis used to determine the attenuation properties.

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The present investigation deals with synthesis of graphene oxide (GO) and fabrication of GO-based hybrid nanocomposites (Ncs). Relative to samples from the American Gut Project, fecal samples from PD patients were enriched with Klebsiella and Bacteroides and were depleted of anaerobic taxa (eg, Roseburia and Faecalibacterium). Impedance as a method to sense proximity at the electrode-retina interface. Triplopia is a rare complaint that, in a neurology inpatient service, often represents an unusual interpretation of abnormal eye movements.

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These findings are consistent with expectations based on empirical findings in the broader personality literature linking the construct of disinhibition with externalizing psychopathology as well as the literature identifying callous-unemotional aggression as a risk factor for violence. Use of the CVCs for administration of tracer and subsequent blood sampling would be less distressing for patients (particularly paediatric) and would reduce the frequency of failed samples due to poor venous access. The present study compared the effects of aerobic endurance training at different intensities and with different methods matched for total work and frequency. Neuronal basis of innate olfactory attraction to ethanol in Drosophila. The aim of this study was to evaluate the effect of introducing ROSA by BMS in an outpatient clinic setting.

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To determine the distribution of central and peripheral corneal thickness values and its determinants in an Iranian population. A space resembling the fibro-osseous canal was formed around the tendon after removing the sheaths.

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Septal perforation repair without intraoperative mucosal closure. This noninterventional surveillance study shows IV gadoteric acid to be a safe and effective contrast agent for use in MR mammography.

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Use of splenic artery embolization (SAE) in their splenic injury algorithm. Intercondylar synovial septum in two patients with nail-patella syndrome. The presentation of pseudo-words served as a reference condition. To determine the possible role of collagen II precursors in the formation of the extracellular matrix of the vitreous humour these collagen molecules were purified and in vitro fibrillogenesis was used to demonstrate that pN-collagen II could form fibrils in mixtures with collagen II. Current possibilities for prevention of dysentery in white piglets and calves in mass maintenence of these animals

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SLD protein was isolated and resolved by two-dimensional gel electrophoresis and analyzed through MALDI-TOF/TOF-based mass spectrometry. The results are nonetheless consistent with those obtained in western countries in studies of children with various levels of prenatal alcohol exposure and various levels of fetal alcohol spectrum disorder. Factors influencing the direct actions of volatile anesthetics on airway smooth muscle.

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To test strategy interactions across sequential choices, we utilized various two-choice spatial navigation tasks administered on the Opposing Ts maze, an apparatus for rodents that permits experimental control over strategy recruitment. Iron deficiency anemia (IDA) is the most common form of nutritional anemia worldwide. Anti-GFP immunohistochemistry revealed that a number of neurons in the intermediate and deep layers of the right superior colliculus were positively stained, indicating eTeNT expression.

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Eighteen of these genes have not been associated previously with plaque instability, including the metalloproteinase, ADAMDEC1 (approximately 37-fold), retinoic acid receptor responder-1 (approximately 5-fold), and cysteine protease legumain (approximately 3-fold). Recently, dynamic nuclear polarization enhanced nuclear magnetic resonance (DNP/NMR) has emerged as a powerful technique to obtain significant enhancements in spin spectra from biological samples.

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This study aimed to determine the association of cardiac fibrosis with the galectin-3 (Gal-3) expression, a fibrosis marker in the myocardium and to compare plasma Gal-3 levels in normal and degenerative mitral valve disease (DMVD) dogs. It occurs mainly as peripherally localized, cephalic, or abdominal pain and is usually associated with a symptomatic etiology. Finally, EFL1 did not down-regulate protein expression of ABCB1. School settings have been pointed out as potentially effective settings for prevention. Clinical and biochemical investigations to evolve early diagnosis in workers involved in the manufacture of hexachlorocyclohexane.

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The HP hydrogel exhibits both sustained drug release behavior and superior bioavailability in physiological conditions. SKF 38393 enhanced the preference, whereas quinpirole eliminated it. Intermediate temperature proton conductors for PEM fuel cells based on phosphonic acid as protogenic group: a progress report.

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This study investigated whether estradiol modulates the anti-apoptotic signal through the phosphorylation of Akt and its downstream targets, including Bad, forkhead transcription factors FKHR and FKHRL1. Pili annulati is a rare autosomal dominant hair disorder clinically characterized by a pattern of alternating bright and dark bands of the hair, the bright bands appearing dark if observed by transmitted light. Specific Noncompetitive Immunoassay for HT-2 Mycotoxin Detection. More deaths occur in African women from invasive cervical cancer (ICC) than from any other malignancy. Further, intensifying ongoing health education, continuous monitoring and evaluation, and integrating the voucher program with other services is likely to address some of the barriers.

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To investigate the effect of magnesium sulfate and its interaction with the non-depolarizing muscle relaxant vecuronium at adult muscle-type acetylcholine receptors in vitro. The benefit of fusion systems in focal therapy of prostate cancer (PC) is less clear.

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Data on efficacy, acceptability and tolerability were extracted and the quality of the trials was assessed. Nipple-areola complex sparing mastectomy with periareolar pexy for breast cancer patients with moderately ptotic breasts. Cadherins and catenins are CAMs that are located on the cell membrane and are important for adherens junction (AJ) function. Demographic data (age, gender, nationality) and medical data (mechanism of injury, final diagnosis, hospital admission, mortality and medication on admission) were included.

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Immunohistochemical stains for perforin were performed using a monoclonal antibody against human perforin. On the influence of isonicotinic acid hydrazide on the endogenous metabolism of mycobacteria From this study, we conclude that development of (pre-malignant) breast tumors in either wild type or MMTV-cyclin D1 mice was not augmented due to mammary gland targeted overexpression of human cortactin. The majority of the suture anchor fixations and the screw fixations were failed by pull-out from the bone.

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The toxic and hemagglutinating components of the crystalline toxin of Clostridium botulinum were analyzed for their amino acid content and were proven to be completely different proteins. The future of endovascular treatment: Insights from the ESCAPE investigators. Variables such as pain severity, pain of cheek region, pain frequency, tenderness of masticatory muscles, click, and mouth opening were evaluated at each stage.

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In the tan Rpe65-/- mice, the level of photoreceptor degeneration is less than in the agouti animals, which have an increased pigment and decreased free opsin level. We conclude that the mutant htt peptides that accumulate in pathologic structures of human HD and httN171-82Q in mice are produced by similar, yet to be defined, proteolytic events in a region of the protein near or within amino acids 90-115.

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Implications for substantive research, strengths and limitations, and directions for future research are offered. Reward and punishment sensitivity in women with gambling disorder or compulsive buying: Implications in treatment outcome. The pharmacokinetic properties of epirubicin are characterised by a triphasic plasma clearance, with half-lives for the initial (alpha), intermediate (beta) and terminal (gamma) elimination phases of approximately 3 minutes, 1 hour and 30 hours, respectively. Do lesional perfusion abnormalities on arterial spin labeling truly contribute to the diagnosis of Leigh syndrome? The estimates presented in this study can be used to establish a baseline for monitoring trends in EHR use among RCCs.

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Autonomic modulation of heart rate of young and postmenopausal women undergoing estrogen therapy. Rat dams were treated with CBZ during pregnancy and breastfeeding. Interpretation of a pumping test with interference from a neighboring well. The last layer of each cavity is very sensitive to the monitor passband width, showing that the monitor passband width of an optical monitor should be less than half the designed passband width. Local accumulation of ammonium in CNS, that may remain undetected in plasma and urine, may therefore play a key role in the neuropathogenesis of methylmalonic aciduria both during acute decompensations and in chronic phases.

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Diagnostic performance of index tests was compared by the summary area under receiver operator characteristic curve (AUROC). Reliable synthesis and characterization of these materials must be developed if these properties are to be exploited. Transforming ability of bacterial deoxyribonucleic acid in relation to the marker efficiencies in Diplococcus pneumoniae during thymidine starvation. At hatching, 3 and 7 d of age, 16 goslings (8 males and 8 females) were used. Trials calculating ECV from multiple blood samples, after longer equilibration times, or using other tracers did not find a contraction of the ECV.

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The hydroethanolic extract of Piper aduncum and its component proteins increased the proliferation and migration of hDFa and increased the expression of growth factors involved in the healing process. A literature search on PubMed for the MeSH terms for percutaneous nephrolithotomy (PCNL), ureteroscopy with lithotripsy, shock wave lithotripsy (SWL), and laser lithotripsy, published in English between January 2007 and January 2010 was performed. To our knowledge, this patient cohort represents the largest series of comprehensive computer aided free-flap reconstruction with dental restoration for giant type ameloblastoma.

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Mental Health First Aid is a relatively new concept conceived in Australia about 10 years ago and by 2010 it has spread to 15 other countries including Nepal. Cell apoptosis was observed by fluorescence microscope and measured with flow cytometry and Cytochrome C ELISA kit. Here, we present novel observations about the course of light-induced retinal degeneration in BALB-c mice exposed to 1500 lux during 4 days with or without treatment with tezosentan, a mixed endothelinergic antagonist.

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Ultrastructural disorder of actin mutant suggests uncoupling of actin-dependent pathway from microtubule-dependent pathway in budding yeast. A sixteen-year-old boy presented to our outpatient clinic with difficulty in walking due to swelling of both ankles.

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The present results demonstrate that the serotonergic raphe-hippocampal and the GABAergic septohippocampal pathways are able to modulate dendritic inhibition of principal cells via calretinin-containing GABAergic interneurons. Calcification of the ascending aorta, arch, carotid, and coronary arteries was quantified. The pharmacokinetics of antimony were assessed in the blood and in organs of the mononuclear phagocyte system and compared to those achieved with the free drug and the drug encapsulated in large sized liposomes (mean diameter of 1200 nm).

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Erythrocyte osmotic fragility testing and the prediction of canine malignant hyperthermia susceptibility. Neuroprotective effect of carvedilol against aluminium induced toxicity: possible behavioral and biochemical alterations in rats. A new bovine Y-specific fragment revealed by DNA fingerprinting. Inhibition of skeletal muscle S1-myosin ATPase by peroxynitrite. The RNA was subject to Northern hybridization and RNase protection assays and it was concluded that the two genes are transcribed separately.

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Remarkably, lethal injections are administered remotely and neither physicians nor other execution personnel assess depth of anesthesia prior to injection of the painful lethal drugs. A database was collected during the 24-month period recording cases with irretrievable LightspeedLSX separation. Virally mediated membrane changes: inverse effects on transport and diffusion.

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A functional interaction of TFIIB with p65 was evident from assays in yeast cells. SI of the TPLO group were not different from the normal control group by 6-12 months postoperatively. International medical journals cannot rectify global inequities, but they have an important role in educating their constituencies about the global divide. The assignment of significantly changed NMR signals, which were identified with the help of multivariate models, to individual metabolites in biofluids is a manual and tedious task requiring knowledge in chemometrics and NMR spectroscopy.

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Gold aggregating gold: A novel nanoparticle biosensor approach for the direct quantification of hepatitis C virus RNA in clinical samples. Stridor is a noise caused by the passage of turbulent air through a diminished airway caliber. The results therefore support earlier evidence against a sensory cholinergic synaptic link. Scopolamine in acute intramuscular doses of 0.25-0.75 mg reduced the P2-N3 flash-VEP amplitude and, in the quantitative EEG, the 8.5-12.0 Hz power and total power in 8 healthy young male volunteers.

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However, these techniques are found to have only temporary beneficial effects. A systematic study of C-glucoside trisphosphates as myo-inositol trisphosphate receptor ligands. Coherent x-ray wavefront reconstruction of a partially illuminated Fresnel zone plate. A total of 50 Danish departments of anaesthesia and 30 societies of anaesthesiology were invited by e-mail to detail their guidelines on pre-anaesthesia ACE inhibitor and ARB use and the number of registered deaths due to hypotension.

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In most epidemic prevalence scenarios, RDTs would considerably reduce over-treatment for only a moderate increase in costs over presumptive diagnosis. After a very long and windy road, in December of 2005 the FDA approved CTLA4Ig for the treatment of rheumatoid arthritis. This review summarizes the various analytical methodologies in which SNPs are used and presents examples of how each of these methodologies have been used to locate genes and genomic regions of interest for various cancer types.

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In rural Malawi, 840 6-month-old healthy infants were enrolled to a randomised trial. Bone marrow histological and whole-body (WB) MRI findings served as the reference standards. The differential diagnosis between DSPD and conventional psychophysiological insomnia is important for correct therapeutic intervention. Furthermore, the preliminary result of contrast enhanced ultrasound (CEUS) was analyzed. The results of the kinetic investigations are consistent with the identification of key interactions in the structural models and demonstrate that enantiospecificity is coordinated by the interactions of a number of residues in RdpA and SdpA.

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Oral isotretinoin therapy was successfully used for the inhibition of sebaceous gland proliferation. The posterior primordium, which deposits the neuromasts on the body and tail of the embryo, migrates along the horizontal myoseptum from the otic region to the tip of the tail.

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Current programs to address these barriers include language assistance services, community engagement strategies, cross-sector collaboration, and community assessments. Recent research has looked at learning gains and acceptability of online material in medical education as well as specific models that can be implemented to address the challenges. Interleukin-12 receptor beta1 IL12RB1 deficiency causes vulnerability to poorly virulent mycobacteria and nontyphoid Salmonella species. The 50th anniversary of the Brazilian Academy Neurology (BAN) is being celebrated. Awareness among health care professionals of the potential of these children and tailored psychosocial interventions might improve socioprofessional development.

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For children with a postaxial deficiency with a femur that is too short for lengthening, and with a stable ankle and foot with good function, rotationplasty offers the best functional outcome. The rate of leaving hospital AMA did not systematically change over time, but did vary based on patient and illness characteristics. Lung, kidney, brain, and the reproductive system contain relatively high levels of CPM, but its functions in those tissues are largely unknown. Although the freeze-all policy may be related to better in vitro fertilization (IVF) outcomes in normal responders, these potential advantages decrease with worsening ovarian response.

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The receptor is overproduced by a number of malignant cell lines in vitro and in a large percentage of ovarian and uterine malignancies. Superfamily 1 helicases are dermabel gel es bueno nucleic acid motor proteins that couple ATP hydrolysis to translocation along, and concomitant unwinding of, DNA or RNA. This study explores how stroke survivors managed their lives, gave meaning to their self-management post-stroke and how this evolved over time. Pain was concentrated over the dorsum of the foot in both weight bearing and at rest. Excluded articles included 27 articles in languages other than English, 18 commentaries or reviews, and 67 irrelevant articles.

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We conclude that CLP caused rapid diminution of luteal function which was accompanied by a reduction in P4 content but not in P4 concentration. Country experiences show that IPT can be introduced and scaled up relatively quickly and effectively where there is political will, effective integration between malaria and reproductive health programmes, adequate funding and drug supply, high ANC attendance and community receptiveness. Can we discontinue synthetic disease-modifying anti-rheumatic drugs in rheumatoid arthritis? Pressure ulcers are debilitating wounds that arise frequently in people who have lost mobility. Different groups worldwide have designed and evaluated new efficient protocols for the isolation, expansion, and maintenance of clinically safe human DPSCs in sufficient numbers for various therapeutics protocols and have discussed the most appropriate route of administration, the comenter mirtazapina 30 mg possible contraindications to their clinical use, and the parameters to be considered for monitoring their clinical efficacy and proper biological source.

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Agitation of the solvent in furosemide dosage canine tablet dissolution studies--a flow visualization technique. Usefulness of endobronchial ultrasonography with real-time needle aspiration for lung cancer staging

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Triglyceride-rich lipoproteins are causally associated with high risk of ischemic heart disease (IHD), and apolipoprotein E (apoE) has a central role in their plasma clearance. We searched MEDLINE, Embase and Cochrane Library Databases for published 3 mg clonazepam high feeling studies. Its utility for clinical decision making and its biologic role in endometrial cancer deserves further study in a larger series of patients.

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It remains unknown whether laryngeal/respiratory coordination of phonation for speech relies on separate neural systems from respiratory control or whether a common system controls both behaviors. Effects of vigorous walking exercise on core body temperature and inhibitory control in thermosensitive difference between rebetol and copegus manufacturer persons with multiple sclerosis. Epidermal growth factor receptor mutations in non-small cell lung cancer: a basic science discovery with immediate clinical impact.

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Mice infected with virulent Mycobacterium tuberculosis exhibit an age-related increase in susceptibility to disease. Laser Doppler perfusion imaging was performed to measure perfusion of these areas at 1, 2, and fougera clindamycin phosphate gel usp 1 reviews 6 weeks.

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Realistic modeling is a new advanced methodology for investigating brain functions. The objective of this investigation was to develop a disease model to predict measures of headache in randomized placebo-controlled clinical trials investigating oral sumatriptan as a paradigm compound. Recently, models for both stages have been extended with the development of distributed lag non-linear models (DLNMs), a methodology for investigating simultaneously non-linear and lagged relationships, and multivariate meta-analysis, a salicrem forte music methodology to pool estimates of multi-parameter associations. There remains considerable debate regarding the limiting factor(s) for maximal oxygen uptake (VO2max).