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Calcium plus vitamin D3 supplementation for 12 weeks augmented body fat and visceral fat loss in very-low calcium consumers during energy restriction. Despite administration of systemic corticosteroids after biopsy, the intraocular mass was not reduced. Physical changes that impose cosmetic and appearance challenges can be psychologically immobilizing for women with cancer. Although the pros and cons for each sequencing mechanism have more or less been discussed in a number of occasions, the potential obstacle imposed by palindromic sequences has not yet been addressed. Our findings suggest they do and that an osteoporotic bone environment may increase sensitivity to BMP-7.

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Addition of DNA destabilises complexes between p50 and ankyrin repeat containing proteins, increasing the susceptibility of the nuclear localisation signal to trypsin cleavage. Special application of fluorescence histochemistry: studies on eight monoamine oxidase inhibitors in brain neurons. A new pathway for biosynthesis of anthraquinones: incorporation of shikimic acid into 1,2-dihydroxyanthraquinone (alizarin) and 1,2,4-trihydroxyanthraquinone (purpurin) in Rubia tinctorum L

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Major glycoproteins in carp CNS myelin: homology to P0 protein with HNK-1/L2 carbohydrate epitope. Emphasis is given here on the estimation of nutrient loads and on the study of the N/P ratio in the water body.

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There was moderate (KDIGO) to high prevalence (KDOQI) of CKD-MBD among the patients. Past efforts at curing infection with the human immunodeficiency virus (HIV) have been blocked by the resistance of some infected cells to viral cytopathic effects and the associated development of a latent viral reservoir. Ascorbic acid levels in mammalian tissues and its metabolic significance. Therefore, it is important to include IVC aneurysm as a differential when patients present with unprovoked DVT. Granulocyte macrophage-colony stimulating factor induced Zn sequestration enhances macrophage superoxide and limits intracellular pathogen survival.

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These results suggested that ultrasound detected early cerebral edema better than MRI did. A very significant difference occurred in pathologic adhesion scores favoring the ultrasonic scalpel when the animals were treated with saline. Regulation of fat metabolism in hunger and in re-feeding with carbohydrates Thus, we performed a meta-analysis to determine its impact and to evaluate factors to increase its risk.

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Anti-alpha-galactosyl immunoglobulin A (IgA), IgG, and IgM in human secretions. Discretized data pattern in endoscopic gastritis images using Dynamic Window and Pairwise Gini Criterion. Agent-based model of epithelial host-pathogen interactions in anastomotic leak. The other cells had BoCD4 or BoCD8, but rarely gamma delta T cell markers.

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A review of the phenotypes of the patients known with this chromosome deletion is presented. An extremely rare portal annular pancreas for pancreaticoduodenectomy with a special note on the pancreatic duct management in the dorsal pancreas. The objective of this study is to examine practice-level variation in rates of guideline-recommended treatment for outpatients with heart failure and reduced ejection fraction, and to examine the association between treatment variation and practice site, independent of patient factors. The activities to be administered result in weight-independent effective doses to the children. Efficiently Visible-Light Driven Photoelectrocatalytic Oxidation of As(III) at Low Positive Biasing Using Pt/TiO2 Nanotube Electrode.

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This includes both tacit knowledge (personal experience) and explicit knowledge (evidence). The complexity of neurosurgical procedures and their interactions with maternal and fetal physiologies are key factors in determining the overall maternal and fetal outcome.

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The spatial distribution of tropospheric and stratospheric temperature trends for 1979 to 2005 was examined, based on radiances from satellite-borne microwave sounding units that were processed with state-of-the-art retrieval algorithms. ShortStack is a program that was developed to comprehensively analyze reference-aligned small RNA-seq data, and output detailed and useful annotations of the causal small RNA-producing genes. Lymphatic metastatic characteristics of oral squamous cell carcinoma are not fully understood, for instance, skip metastasis is still controversial.

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Chitin is the most abundant aminopolysaccharide polymer occurring in nature, and is the building material that gives strength to the exoskeletons of crustaceans, insects, and the cell walls of fungi. To assess the pain-relieving effects of motor cortex electrical stimulation (MCS) and the predictive factors retrospectively. This study was comprised of a literature review and interventional case report.

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In contrast, higher concentrations of EGCG (100-400 microM) do not induce apoptosis, but rather trigger necrotic cell death in MCF-7 cells. Departments of Ophthalmology, Columbia University and New York University School of Medicine, New York, New York, USA.

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Interaction of hydrogen with RuO2(110) surfaces: activity differences between various oxygen species. Demographic and laboratory variables were analyzed to identify significant risk factors. Endogenous targets of RNA-directed DNA methylation and Pol IV in Arabidopsis.

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It has a high interrater reliability and face validity and correlates with future citations. Significantly, early breast cancer screening never seemed to be cost-effective in women with only one affected first-degree or second-degree relative. Urethral fistula is rare and is usually a complication of penile and urethral surgery.

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Observing and improving hand hygiene compliance: implementation and refinement of an electronic-assisted direct-observer hand hygiene audit program. In both studies, antibodies developed after 4-6 administrations of rhFVIII, and neutralizing antibodies reached levels similar to human patients (range 1-111 BU, median 6.0 BU) at the end of the study.

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Features indicating sacroiliac joint inflammation on MRI are weighted equally to structural changes on conventional radiography, and thus MRI has become an important tool for use in daily practice to evaluate patients with clinically suspected early spondyloarthritis. The interpositional vein is transferred to the vessels of the recipient site primarily, forming an arteriovenous shunt. Shifting concerns away from survival and back to quality-of-life issues has led some of these patients to seek aesthetic surgery. This scale had convergent validity with other measures of fatigue and was able to identify cases of fatigue that met criteria on the FACIT-F.

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To explore the clinical dose of Xiyanping injection, and find the relationship between dose and age. One of the transitional epitopes identified (E2 residues 200 to 202) lies in the E2 190-216 region, which harbors two major neutralization sites, E2a and E2b, and an N-linked glycosylation site at E2 196.

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Immunohistochemical study with a battery of specific antibodies was used. Importantly, we show that although D1 receptor-mediated functions are preserved and even enhanced in D2R-/- mutants, the behavioral response to acute cocaine administration is severely altered. We examined the fibrotic response in small and large myocardial infarct, and the effect of overexpression of the SERCA2a gene. We developed a novel therapeutic strategy of intravenous VNS (iVNS) and examined whether iVNS administered prior to coronary reperfusion in a canine AMI model reduces infarct size and prevents heart failure. Two-dimensionally self-arranged protein nanoarrays on diblock copolymer templates.

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Here, I discuss how key immune cell types (natural killer cells, macrophages, dendritic cells, and T cells) are either enriched or excluded from the decidua, how their function is regulated within the decidua, and how they variously contribute to pregnancy success or failure. However, three-compartment models which account for restriction parallel to the axons and incorporate pore size explain the measurements most accurately.

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The combined analysis of loci detected by genome-wide association studies (GWAS) in 22 inflammatory diseases has revealed a shared genetic core and associated biochemical pathways that play a central role in pathological inflammation. This paper presents a study concerning the application of the LCA methodology to support the development of the new waste management plan for the Bologna District. Nav channel clusters near the nerve terminal and their location as a function of neuronal position along the mediolateral axis are controlled by auditory inputs after hearing onset.

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Heteroaggregation and sedimentation rates for nanomaterials in natural waters. Phytohormone production endowed with antagonistic potential and plant growth promoting abilities of culturable endophytic bacteria isolated from Clerodendrum colebrookianum Walp. Molecular imaging poses both threats and exciting opportunities for radiologists. Among the lipids, the main compounds identified by GC/MS of the hemp fibers extracts were series of n-alkanes, free and esterified sterols and triterpenols, waxes, and long-chain n-fatty acids.

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The concomitant increase in superoxide dismutase (EC 1.15.1.1) and ascorbate peroxidase (EC 1.11.1.7) may have alleviated the photoinhibition caused by the increased level of ROS in sense plants. These novel data in skeletal muscle demonstrate that local expression of FNDC5 is associated with mRNA expression of IGF-I and mitochondrial function and mitochondria-related gene expression in obese subjects with reduced growth hormone and suggest a potential role for FNDC5 acting locally in muscle in a low GH state.

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Substantial differences in SES between the sample visiting the hospital and the broader community suggest a need for community-based sampling approaches in future trauma research. Spectrally engineered broadband photon source for two-photon quantum interferometry. All 4 patients who required repeat ORIF had worrying signs and symptoms despite the immediate postoperative radiograph looking favourable. The aim of our study was to evaluate the validity of four risk scores (Pneumonia score, A2DS2, ISAN score, and AIS-APS) in a population of ischemic stroke patients admitted in a French stroke unit. In this article, we demonstrate that AD is not a monolithic concept and can be broken down into three well-defined sub-domains assessing confidence at the model, prediction and decision levels, respectively.

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Pneumocephalus is a rare condition, characterized by the presence of gas in the cranial cavity, resulting from trauma, tumors and surgical or diagnostic procedures. This study is a retrospective chart review of 3 elite athletes with severe back pain and sacral facet fractures. On tasks involving emotional facial expression, the opposite results were observed: The LI children were more dramatic in their expression of facial affect than were the controls. Sorafenib is efficacious and tolerated in combination with cytotoxic or cytostatic agents in preclinical models of human non-small cell lung carcinoma.

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We demonstrate high detection sensitivity (femtomole quantities of antigen), high specificity (specific detection of antigen directly in serum), high accuracy, and high speed (minutes per assay), surpassing conventional analytical methods by more than 2 orders of magnitude. Disparity in Outcomes for Adolescent and Young Adult Patients Diagnosed With Pediatric Solid Tumors Across 4 Decades. This process involves both the staged activation of T-cell identity genes and the staged repression of progenitor-cell-inherited regulatory genes once their roles in self-renewal and population expansion are no longer needed. NICE has published its first public health guidance documents on smoking cessation and physical activity. PET scan: a more definitive assessment modality for oral cancer.

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Chronic oral exposure to bisphenol A results in a nonmonotonic dose response in mammary carcinogenesis and metastasis in MMTV-erbB2 mice. An investigation into the adjuvanticity and immunogenicity of zein microspheres being researched as drug and vaccine carriers.

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To better define the pattern of cytokine synthesis in this disease and to relate it to the immune activation state, we measured circulating levels of soluble tumor necrosis factor receptor p55 (sTNFR-55) and neopterin in a group of 85 patients with AC (classified according to the Child-Pugh score of severity of liver disease) and 43 healthy volunteers. In a placebo-controlled study of once-weekly darbepoetin alfa treatment in anaemic cancer patients undergoing chemotherapy, significantly fewer treated patients required RBC transfusions, regardless of initial haemoglobin levels. They represent a new transplantation field, with only a 10-year experience and just over 50 clinical cases. Hemodynamic forces induce various changes in the structure and function of vascular endothelium, many of which reflect alterations in gene expression.

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Angiomyofibroma of the nasal cavity: a clinical and electron micrographic study. Information entropic analysis indicates that the residues D309, D222 and D476 have more conformational flexibility compared to E302 and E245 prior to substrate binding. Individual topography of MIC should be determined during the preoperative radiological examination and surgical procedures in the anterior region of the mandible.

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In permeabilized cells, perinuclear staining was observed for both wild-type and mutants. Albuminuria: a target for treatment of type 2 diabetic nephropathy. Although process-based models are commonly used in exposure assessment, the assessment of effects usually comprises purely descriptive models and rules-of-thumb.

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This gaping reaction is suppressed by pretreatment with the antiemetic agent, Delta 9-tetrahydrocannabinol, but not ondansetron (Experiment 2). Our results demonstrate that increased plasma cortisol induced by a slow-release implant of cortisol mimics the overall effects of stress and affects the expression of the three CRs, generating different transcriptional patterns in a time- and organ-specific manner. Incremental validity of Useful Field of View subtests for the prediction of instrumental activities of daily living. Quantitative PCR (qPCR) was used to target three different genes encoding resistance to tetracycline (tet(A), tet(X), and tet(W)), the gene encoding the integrase of class 1 integrons (intI1), and total bacterial abundance (16S rRNA genes) as well as total and human fecal contamination levels (16S rRNA genes specific to the genus Bacteroides ). All of the synthesized films were single-phase CuO nanorods of variable diameter between 80 and 200 nm.

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We present the morphological landmarks during early leg development. There is no apparent correlation between PPRibP concentration and inorganic phosphate, the energy status of the cell, or the hepatic PPRibP synthetase (EC 2.7.6.1.) activity. Finally, we demonstrate that upregulation of atm, and thus Tis-21, in confluent Tac-2 cells can be inhibited by an E-cadherin antibody blocking specifically homophilic E-cadherin interactions between adjacent cell surfaces. The obtained malignant/benign phenotype prediction was also valid for 37 of 54 cases of nodules with undetermined cytology with a total of 8 false positive and 9 false negative predictions.

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Conversely, AREG but not FSH induced Ptsg2 mRNA at 0.5 h with peak expression of Ptgs2 and Areg mRNAs at 4 h, processes blocked by the EGF receptor tyrosine kinase inhibitor AG1478 (AG), PD98059, and NS398. About turn: how object orientation affects categorisation and mental rotation. Statistical consequences of applying a PCA noise filter on EELS spectrum images.

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An electronic hospital database was used to retrospectively identify individuals that were HIV-positive and had bariatric surgery between 2003 and 2013. Combining angioplasty with percutaneous microwave ablation may represent an alternative method for the treatment of BCS associated with HCC. Immunohistochemical expression of CD10, Bcl- 2, Bcl-6, Ki-67 and MUM 1 was performed using paraffin blocks of DLBCL.

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Following unilateral brain injury, patients are often unable to detect a stimulus presented in the contralesional field when another is presented simultaneously ipsilesionally. The influence of substitution in phenylacetic acids on their performance in the buccal absorption test. TB caused less retinal degeneration, mainly in the area detached by the subretinal injection.

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Using methods from time-series analysis, we are able to approximate nonlinear models that allow for long-term predictions and the possibility of developing control algorithms. Dogs with high-grade second-degree AVB had a duration of survival similar to that of dogs with third-degree AVB. Retention in care is more strongly associated with viral suppression in HIV-infected patients with lower versus higher CD4 counts. Clinical practice guidelines for healthy eating for the prevention and treatment of metabolic and endocrine diseases in adults: cosponsored by the American Association of Clinical Endocrinologists/the American College of Endocrinology and the Obesity Society: executive summary. Evaluation of the in vivo therapeutic properties of (-)-cubebin and (-)-hinokinin against Trypanosoma cruzi.

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Pre-arthroplasty simultaneous maxillomandibular distraction osteogenesis for the correction of post-ankylotic dentofacial deformities. This biasing reduces the available resolution in this experimental arrangement.

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Interestingly, overexpression of METTL22 in HEK 293 cells displaces Kin17 from the chromatin to the cytoplasmic fraction, suggesting a role for methylation of lysine 135, a residue that lies within a winged helix domain of Kin17, in regulating association with chromatin. However, baseline neuropsychiatric symptoms did not significantly correlate with decline in other cognitive domains. Genotyping of a total of 127 Cameroon sheep in 7 other flocks by duplex PCR did not identify additional carriers of the deletion. Arterial switch for pulmonary venous obstruction complicating Mustard procedure.

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Ovulation compensatory function after unilateral ovariectomy in dogs. Eight patients with vocal process granulomas refractory to a variety of prior treatments including surgical resection, proton pump inhibitor therapy, and voice therapy underwent percutaneous injection of botulinum toxin type A into the interarytenoid muscle, performed in an office setting. To review the clinical characteristics of patients presenting after centipede bites in Hong Kong. The objective if this study was to identify the IGF-1Ec forms or processing product(s), other than mature IGF-1, generated in different human and rodent tissues and particularly in human skeletal muscle after exercise-induced damage. Charcot-Marie-Tooth disease (CMT) is the most common inherited peripheral neuropathy and is a genetically and clinically heterogeneous disorder.

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The T-cell receptor (TCR) interaction with antigenic peptides (p) presented by the major histocompatibility complex (MHC) molecule is a key determinant of immune response. Regulation of isocitrate dehydrogenase from thiobacullus thiooxidans and Pseudomonas fluorescens.

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Qualitative research has the potential to inform and improve health care decisions but a study based on one year of publications suggests that it is not published in prominent health care journals. Treatment of multiply relapsed wilms tumor with vincristine, irinotecan, temozolomide and bevacizumab. Data were collected from the SAFE card reports and the online reporting systems during introduction, removal, and reimplementation of these cards.