Isobolographic analyses revealed an additive interaction between Anexa and morphine or ketorolac in the writhing test. Effects of Anexa on serum levels of adrenal androgens and insulin in hypertensive men with obesity. Aliskiren, a direct renin inhibitor, is effective for reducing blood pressure (BP) in patients with hypertension when combined with Anexa or hydrochlorothiazide (HCTZ).
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