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Ascool (Labetalol)
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Labetalol

In a multicentre, double-blind, crossover, placebo-controlled study, the antihypertensive effect of Ascool 100 mg and chlorthalidone 10 mg, given alone or in combination, has been assessed in 32 hypertensive patients. Methyldopa, Ascool, nifedipine and diltiazem are considered safe, whereas angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers should be stopped before or at confirmation of pregnancy.

Other names for this medication:
Labetalol, Trandate, Albetol, Ascool, Normodyne, Normozide, Presolol,

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Ascool injection is used to treat severe high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Solution

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Biologic and pharmacologic augmentation of rotator cuff repairs. The Srxn1-GFP reporter is preferentially induced upon oxidative stress and is part of the nuclear factor (erythroid-derived 2)-like 2-antioxidant response pathway. Local structure at the air/liquid interface of room-temperature ionic liquids probed by infrared-visible sum frequency generation vibrational spectroscopy: 1-alkyl-3-methylimidazolium tetrafluoroborates.

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Patients had received a detailed paediatric and child psychiatric assessment, including the Child Behavior Checklist questionnaire. Approximation-based common principal component for feature extraction in multi-class brain-computer interfaces. Leukocyte chemokines such as interleukin (IL)-8, interferon gamma-induced protein-10 (IP-10), regulated upon activation, normal T-cell expressed and secreted (RANTES), and eotaxin are involved in leukocyte recruitment. In a soft-core case, the fifth-order Raman signal indicates that the system consists of the delocalized and localized modes, and only the delocalized mode affects the dramatic change of the fifth-order Raman response functions between solid and liquid phases through nonlinear polarizability. Effects of buffer composition, temperature, pH, and bead surface on phagocytic rate are described.

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Offlabel therapeutic alternatives, including a single dose (2 g/kg) of intravenous immunoglobulin (IVIG), intravenous iloprost 2 ng/kg/min over 6 h for 5 days and, approximately 4 wk later, oral bosentan 37.25 mg twice daily for 4 wk followed by 62.5 mg twice daily for 8 wk, were added to the conventional regimen to treat the serious cutaneous manifestations. Moreover, blockade of these TRP channels significantly ameliorates experimental pancreatitis. The array CGH is the most effective method available to complement cases where chromosome analysis, a gold standard in prenatal diagnosis, proves to be insufficient. A phase III trial showed interesting results in a subset of patients that received docetaxel consolidation prior to randomization to gefitinib or placebo.

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Influence of scars on body image consciousness with respect to gender following laparoendoscopic single-site versus conventional laparoscopic surgery. Since 2011, California has transitioned PLWHA to Medicaid managed care (MMC) and to the Low-Income Health Program (LIHP).

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Assessment of cystatin C and cystatin C-based GFR formulas in reflux nephropathy. The observed structural polymorphism establishes that G-tetraplexes can adopt topologies which project distinctly different groove dimensions, G-tetrad base edges and linker segments for recognition by, and interactions with, other nucleic acids and proteins.

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The multidimensional projection ensures that similar snippets are neighbors in the visual space, but not avoiding overlaps. The oligodeoxynucleotides were bound to the asialofetuin-poly-L-lysine conjugate and this complex was internalized by the cells via asialoglycoprotein receptor, an endocytic receptor unique for hepatocytes. Double-blind, randomized, pilot study assessing the resolution of postburn pruritus. The aim of this study was to evaluate the tissue reactions of solid poly(ortho ester) (POE), histologically and immunohistochemically. The original kidney disease has an effect on renal allograft function and graft and patient survival.

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Needle tip position may have a direct influence on clinical outcome following SNRBs. Diagnosis of the disease is difficult because the severity of bone involvement differs and symptoms change according to the age of the patient. High-resolution DEI-CT images show strong contrast and permit visualization of details invisible in clinical radiographs. The identification of novel biomarkers that can be used to predict treatment response would allow therapy to be tailored on an individual patient basis. Phosphorus limitation for the colony formation, growth and photosynthesis of an edible cyanobacterium, Nostoc sphaeroides.

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We find that each of the two antibodies has similar, but nonidentical, discontinuous epitopes that include regions of subdomain 2 encompassing the dimerization interface. Biochemical markers of cerebral ischemia and subsequent inflammation represent a potential diagnostic and predictive modality in acute ischemic stroke. No statistically significant differences were observed between the performance of the Dentaport ZX and Raypex 6 EALs under the in vivo clinical conditions used in this study. We then knocked down Ambra1 expression with transfection with the plasmid expressing the small hairpin RNA (shRNA) targeting AMBRA1, then re-evaluated autophagy in the OVCAR-3 cells subject to cisplatin treatment, and re-determined the sensitivity of OVCAR-3 cells to cisplatin. Both NGF and BDNF increase the expression of cyclin D1 and cyclin-dependent kinase 4 (cdk4), with temporal expression patterns that parallel the proliferation kinetics of their cellular targets.

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coli strains with different RFLP patterns were sequenced completely. These results indicate that parenchymal components predict survival in glioblastoma patients and in particular that the balance between reactive glial populations is important for patient prognosis. Gene transfer of an engineered transcription factor promoting expression of VEGF-A protects against experimental diabetic neuropathy. To describe use of several electronic devices among individuals with traumatic spinal cord injury (SCI). Several experiments were performed to study the mechanism of underexpression.

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A multicenter study of shock pathways for subcutaneous implantable defibrillators. This work will deepen our understanding on the mechanism of both laser ablation of bulk targets in liquid and laser irradiation of particles in liquid.

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The key effects of flow forms on particle motion are the shape and stability of the wake behind the droplet. promising results of IORT in RUC have been observed especially if no irradiation is given during the primary treatment. Erratum: Utility of 18F choline photon emission tomography/computed tomography in the diagnosis of parathyroid adenoma. Inhibition of methane oxidation by ammonium was observed in all samples and depended on methane and ammonium concentrations.

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Next, we find that offices have city-specific bacterial communities, such that we can accurately predict which city an office microbiome sample is derived from, but office-specific bacterial communities are less apparent. To evaluate the correlation between aortic root calcification (ARC) markers and coronary artery calcification (CAC) derived from coronary artery calcium scoring (CACS) and their ability to predict obstructive coronary artery disease (CAD). In order to store and process such a great amount of data, cloud computing and MapReduce were applied to many fields of bioinformatics. Tectal Lesions in Children: A Long-Term Follow-Up Volumetric Tumor Growth Analysis in Surgical and Nonsurgical Cases. Detection of microcalcifications in digital mammograms using wavelet filter and Markov random field model.

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Use of monoclonal anti-light subunit antibodies to study the structure and function of the Entamoeba histolytica Gal/GalNAc adherence lectin. Studies in the Nomenclature and Classification of the Bacteria: V.

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Characterization of genes encoding novel peptidases in the biocontrol fungus Trichoderma harzianum CECT 2413 using the TrichoEST functional genomics approach. Seventeen patients after breast conserving surgery underwent 3D CT simulation scans followed by respiration-synchronized 4D CT simulation scans at free breathing state. Using standard aseptic technique, no contamination of XRC occurred, suggesting multi-dosing may be a safe and cost-effective method of XRC utilization. Degeneration of hepatocytes was obviously prevented in mice treated with dl-THP, and the liver histological structure was well maintained. Extracorporeal life support (ECLS) is applied to refractory pulmonary hypertension in congenital diaphragmatic hernia (CDH).

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Vegas (Verruciform Genital-Associated) Xanthoma: A Comprehensive Literature Review. The progress of pleural plaques in persons exposed to environmental asbestos in Almopia, Greece were studied prospectively. In the pathological state caused by dopamine depletion, the STN-GPe network exhibits rhythmic synchronous activity accompanied by rebound bursts in the STN. The present study was planned to investigate sleep-prolonging effect of C.

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The anisocoria induced by small-aperture approaches to aid presbyopes produces marked interocular differences in visual latency. It is hypothesized that this variant may reflect heterogeneity in the normal population of hairy-cell leukemia cells, and may explain the partial resistance of HCL patients to IFN therapy. Previous research has shown that reminders can be effective for extending and enhancing a variety of kinds of memory in infants.

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A health promoting school approach used to reduce the risks of lead poisoning and to establish cross-ethnic collaboration. Pathway analysis of large-scale omics data assists us with the examination of the cumulative effects of multiple functionally related genes, which are difficult to detect using the traditional single gene/marker analysis.

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Classmode: a new data format for real-time multiparameter data analysis and data compression. We pooled dichotomous data with fixed-effect odds ratio and continuous data with mean difference (MD) using a fixed-effect where possible. Forty patients in the cryotherapy group and 36 patients in the curettage group completed the study period. Superiority of the consensus fuzzy clustering method is demonstrated quantitatively, visually and statistically by comparing it with the previously proposed hierarchical clustered results. Thirty-six Chinese and thirty-two Indian undergraduate students are included in this study.

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Endothelial Notch activation is required for NO production and reactive vasodilation in a femoral artery ligation model. These include physiological state, dose, types of cognitive tasks used and level of cognitive demand. Neutral salt addition compounds of N-methylated glycines: their formulation and that of their hydrates.

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We retrospectively reviewed 2891 consecutive TKAs in 1933 patients. Application of this new tool of high-resolution spectroscopy to photoemission, energy-resolved fluorescence spectroscopy and microscopy has now been made possible with the advent of undulator sources of soft X-rays. ALS patients were characterized by the ALS functional rating scale (ALSFRS-R) and the Edinburgh Cognitive and Behavioural ALS Screen (ECAS).

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Patients with acute-on-chronic liver failure (ACLF) are often highly susceptible to microbial infection due to a depressed immune system. Associations between placental abruption and maternal long-term cardiovascular morbidity and mortality were investigated. Long-chain primary amines are found to be the most efficacious capping agents for CdSe QDs in nonpolar solvents.

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Methotrexate is effective and well tolerated in children with CD. During group meetings experts described the implementation process and created reference modes and causal diagrams that the evaluation team used to build a preliminary model. Sulindac sulfide inhibited 14-3-3epsilon proteins in HT-29 and DLD-1 cells in a time- and concentration-dependent manner. We found that p42MAPK was the major kinase phosphorylating xEIAP/XLX in cytostatic factor-arrested egg extracts, and three Ser residues (Ser 235/251/254) were identified as p42MAPK-mediated phosphorylation sites.

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These results indicate that DHP calcium channels (type L-channel) play a role in some of the pharmacological effects of nicotine, particularly, locomotor activity and antinociception. A polymerase chain reaction-based assay for 9 respiratory viruses was performed on nasal samples. All emotional expressions were rated as more arousing and more pleasant/unpleasant than neutral expressions.

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Feasibility of using the CCCS was demonstrated with reduced survey completion time and ease of administration, and the survey reliably measures knowledge, skill, and attitudes for providing cross-cultural care. Active mTORC1 enhances processes including glycolysis, protein, lipid and nucleotide biosynthesis, and it inhibits autophagy.

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Ligand-free stellated gold nanoparticles (AuStNPs) with well-defined octahedral (O(h)) and icosahedral (I(h)) core symmetries were prepared using hydrogen peroxide as a reducing agent. Electroanatomically estimated length of slow pathway in atrioventricular nodal reentrant tachycardia. Interestingly, individual aGPCRs may undergo additional proteolytic steps, one of them resulting in shedding of the entire ectodomain that is secreted and can function independently.

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Since morphological features of renal cell carcinomas may not always predict their clinical behaviour, other biological parameters are more and more searched for, as prognostic indicators. Study design is critically important when investigating the efficacy of dietary components, and most studies involving older people include rigorous inclusion/exclusion criteria based on medical history, laboratory tests, general health status and often nutritional status. Besides segmenting the gross tumor, we also differentiate between active cells, necrotic core, janimine drug and edema.

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The purpose of this study was to determine whether Pilates is more effective than traditional strength and balance exercises for improving balance measures, balance confidence and reducing falls in community dwelling older adults with fall risk. Consequently, this study compared manfaat obat oxytetracycline hydrochloride gamers and nongamers in task switching ability, visual short-term memory, mental rotation, enumeration, and flanker interference, as well as investigated the influence of self-reported problematic video game use. Correlation of staphylococcal bacteriophage types to L-form colony production.

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