Ezetimibe and Stacor combination is used together with a proper diet to treat high cholesterol and triglyceride (fats) levels in the blood. This medicine may help prevent medical problems (eg, heart attack, stroke) caused by clogged blood vessels. It is also used to treat a condition called homozygous familial hypercholesterolemia (HoFH).

Ezetimibe is a cholesterol absorption inhibitor and Stacor is an HMG-CoA reductase inhibitor, or statin. These medicines will reduce the absorption of cholesterol from foods and the production of cholesterol in your body.

This medicine was available only with your doctor's prescription.

The Stacor/ezetimibe combination (Liptruzet(R)) was withdrawn from the United States market on June 2, 2015.

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The implication of an immunological lymphocyte T phenomena in the pathogenesis of psoriasis has led to research for new treatment options over the past few years. It was also recently found that other immunological targets such as myelin oligodendrocyte glycoprotein (MOG) may be associated with seronegative NMO patients. This second part focuses on the diagnostic options available to identify infected species such as sheep, goats, dogs, cats, and camelids, and highlights the significant challenges posed, both in establishing estimates of disease prevalence and in controlling infections in these species, in the absence of fully validated tests. Treatment with 1 mmol L(-1) CaCl2 led to earlier translocation of NF-kappaB at 24 h after treatment and addition of AM did not abolish the effect of 1 mmol L(-1) CaCl2 on NF-kappaB activation.

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Left and right ventricle inflow velocities were recorded with PW Doppler and DTI studies. Brief report: a brief intervention to improve lifeguard surveillance at a public swimming pool.

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To study the surgical reconstruction of unilateral Craniofacial Atrophy and Hypoplasia. Ageing Effect on Air-Conducted Ocular Vestibular Evoked Myogenic Potential. Mutations in the non-imprinted Prader-Willi/Angelman syndrome locus 1 (NIPA1) transmembrane protein cause an autosomal dominant form of HSP (SPG6).

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To demonstrate the use of a mixed deterministic-probabilistic method of secure and private record linkage (SAPREL)--to describe selection bias in subjects chosen for in-depth evaluation. Ophthalmologists need to be more familiar with this tumour to allow early clinical recognition and diagnosis.

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Effect of uniaxial stretch on morphology and cytoskeleton of human mesenchymal stem cells: static vs. Elevated BIRC6 protein expression may serve as a predictive marker for chemoresistance of NSCLCs and a poor prognostic factor for NSCLC patients. Recent advances have been made by using probes, such as TaqMan probes, to detect amplified products.

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Therefore the monorail balloon was exchanged for an over-the-wire balloon. Noninvasive prenatal testing for aneuploidy using cell-free DNA - New implications for maternal health.

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Complexity of chromosome structure in interphase can be characterized by measuring a statistical property of physical distance between genomic loci according to genomic separation along single chromatids. The system has been used for the production of intracellular proteins in Escherichia coli and can be applied to other expression hosts for the production of secreted proteins or proteins that require post-translational modification. To directly analyze the oncogenic properties of acrogranin, we established an immortalized uterine smooth muscle cell line by transfection of human telomerase reverse transcriptase into primary culture. Genes induced by thyroid hormone (TH) to change their expression in the Xenopus laevis gastrointestinal (GI) tract have been isolated using a subtractive hybridization method.

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A major hindrance of widespread and routine use of rhTSH-stimulated (131)I-therapy is its present status as an off-label treatment. Acetazolamide 125 mg BD is not significantly different from 375 mg BD in the prevention of acute mountain sickness: the prophylactic acetazolamide dosage comparison for efficacy (PACE) trial.

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In cats, mastocytemia is considered to be confined to animals with mast cell tumors (MCT), whereas in dogs it is associated with diverse diseases. Four focus group discussions were conducted, with 23 participants divided into two groups of working and retired adults, and two groups of full- and part-time students selected from inner-city residents of Birmingham, AL, and surrounding counties.

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The neural basis of functional neuroimaging signal with positron and single-photon emission tomography. Despite strong evidence of leadership activities, few leadership-specific outcomes were generated from the primary analysis.

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High-dose chemotherapy produces high complete remission (CR) rates and some survival advantage in patients with metastatic breast cancer (BC). In the ovaries, levels of mRNAs increased from the day 10 post-blood feeding onwards. The study investigators created a library of 99 ultrasound video images of the chest with or without pneumothorax obtained from 53 patients undergoing elective thoracic surgery. OVX-induced bone loss in IL-7-deficient mice was selective and occurred in trabecular but not cortical bone. Modulation of neutrophil activity by nitric oxide during acute myocardial ischaemia and reperfusion.

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RT-PCR was more sensitive than microscopic examination of bone marrow biopsies. The first network of strongly connected regions consists of the occipital place area/transverse occipital sulcus and posterior PPA, which contain retinotopic maps and are not strongly coupled to the hippocampus at rest. To study the specific celluar immune response and protective efficacy induced by co-immunization of DNA vaccine of Mtb8.4 with signal sequence (MS) and plasmid encoding human interleukin 12 (hIL-12).

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Our findings strongly support the existence of the long-term predictability in stock price dynamics, and may offer a hint on how to predict the long-term movement of stock prices. Chromatin structure plays an important role in the regulation of gene expression. These sites appear to act as chromosome-organizing clamps by tethering distant loci to the nuclear periphery, at which TFIIIC is concentrated into several distinct bodies. We searched multiple databases from the date of publication of the truncated trial through August, 2015.

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The study of the Rudin-Shapiro sequence, homometric to random sequences, allows one to manipulate independently two-point and four-point correlation functions, and to show their effect on the statistics of speckle patterns. In clinical practice, physicians often exploit previously observed patterns in coronary angiograms from similar patients to quickly assess the state of the disease in a current patient. Both types of drainage implants provide excellent postoperative IOP control. Adalimumab, at the dose and duration of treatment used in this study, is likely to be an effective and relatively safe suppressive treatment for cutaneous sarcoidosis.

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The DAPROCAdata registers clinical data and selected characteristics for patients with prostate cancer at diagnosis. These considerations are used to propose design requirements necessary to provide appropriate monitoring in all other field conditions. A 70-year-old man underwent a thallium-201 brain SPECT in the work-up and characterization of a frontotemporal mass.

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In this study, we developed a mouse model of primary and secondary influenza infection by using a widely circulating seasonal H1N1 virus and the pandemic strain of H1N1 that emerged in Mexico in 2009, and we evaluated several key issues. Towards a unified paradigm for sequence-based identification of fungi. In spite of the limited number of publications, laser microdissection was shown to be an extremely useful method for studying host-microorganism interactions in animals and plants, investigating bacteria within biofilms, identifying uncultivated bacteria and performing single prokaryotic cell analysis. Among patients admitted for worsening signs and symptoms of HF and reduced EF, congestion improves substantially during hospitalization in response to standard therapy alone.

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Evaluation of histopathological changes in the microstructure at the center and periphery of glioma tumors using diffusional kurtosis imaging. Brief report: approaches to 31P-MRS in awake, non-sedated children with and without autism spectrum disorder.

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Our meta-analysis shows that using topiramate can prevent or reduce weight gain associated with AAPs. We conclude that murine leukemia virus can replicate by using various tRNA molecules as primers and propose primer binding site-tRNA primer interactions to be of major importance for tRNA primer selection. The cost utility of bupropion in smoking cessation health programs: simulation model results for Sweden.

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Stress-induced GC secretion by the adrenal glands initially enhances and later suppresses the immune response. Using UPGMA method all the tested accesions can be clustered into two groups: 4 accessions of Daye were classified as one group, 1 accession of Xiaoye be another group.

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To study the clinical features of invasive pulmonary aspergillosis (IPA) with chronic obstructive pulmonary diseases (COPD), so as to provide evidence for early diagnosis and treatment. After irradiation more melanocytes above the dermal-epidermal junction are observed in seven nevi, simulating a melanoma in situ in three nevi. Murine tracheal segments were cultured up to 8 days in the absence or presence of IL-1beta with subsequent evaluation in a myograph system, along with mRNA quantification, focusing on the role of the epithelium, acetylcholine release, transcriptional mechanisms and MAPK activity. Aberrant p53 expression in astrocytic neoplasms of the brain: association with proliferation. Dehydroindigo: a new piece into the Maya Blue puzzle from the voltammetry of microparticles approach.

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After phagocytosis, Chediak-Higashi syndrome granulocytes displayed a normal burst in oxygen consumption and oxidation of glucose-1-(14)C and glucose-6-(14)C and formate-(14)C. Interactions of concanavalin A with the membrane of infleunza virus infected cells and with envelope components of the virus particle. The coincident localization of SecA(Spn), SecY (Spn), and HtrA (Spn) to regions of peptidoglycan (PG) biosynthesis in unstressed, growing cells suggests that the pneumococcal Sec translocase directs assembly of the PG biosynthesis apparatus to regions where it is needed during division and that HtrA(Spn) may play a general role in quality control of proteins exported by the Sec translocase. Efficacy of an anti-CD5-ricin A chain immunoconjugate in an improved human peripheral blood lymphocyte--reconstituted severe combined immunodeficient mouse model. The kinetic of copper accumulation in the intra and extracellular compartments was determined and correlated to the oxidative burst resulting from copper-mediated oxidative stress.

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This article discusses factors influencing this trend, and explores organizations, systems and programs that have shown promise for reducing maternal morbidity and mortality. Most incidents of high-flow arteriogenic priapism result from genitoperineal trauma, such as that caused by sliding on a wooden bar or falling astride a ladder. To the best of our knowledge, no controlled trial has been carried out comparing the antipyretic efficacy of paracetamol (oral and intravenous) and intramuscular diclofenac in adults. Monoamine concentrations in blood and brain tissues were determined by fluorescence spectrophotometry.

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Proteome identification using peptide-centric proteomics techniques is a routinely used analysis technique. Most of the miRNA targeted genes were predicted to encode transcription factors that regulate cell growth and development, signaling, and metabolism. The ectopically expressed SuSy protein exhibited sucrose-degrading activity, which may change the flux of sucrose demand from photosynthetic to non-photosynthetic cells, and trigger an unknown sucrose signaling pathway that lead to increased sucrose content in the transgenic plants. The mean score for satisfaction was higher among patients who underwent superomedial pedicle rather than the inferior pedicle method.

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A Noise-Filtering Method for Link Prediction in Complex Networks. Surgery had the most profoundly negative effect on HRQOL, seen in both the SC and LC treatment groups to the same extent. Three hundred and seven adolescents (ages 12-17) provided ratings of recognizability, palatability, and desire to eat, for images from the food-pics database. Role of regulatory and proinflammatory T-cell populations in allergic diseases.

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Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion strategy in patients with ST-elevation myocardial infarction (STEMI), but its benefit over prehospital fibrinolysis (FL) is not clear. The goal of our study was to compare the impact of 3 suture materials on perineal pain and on resumption of sexual intercourse. Patient-specific feedback to inner-city providers increased scheduled asthma visits, increased asthma visits in which medications were stepped up when clinically indicated, and reduced emergency department visits. A new mite species of the genus Haemogamasus Berlese is described from the muskrat in Kyrgyzstan. The role of platelet-activating factor on histamine hypersensitivity in nasal allergy in guinea pig models.

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The ability of the time reversal process to reconstruct sources of finite size relative to a wavelength is investigated. Moreover, Experiment 4 demonstrated that increasing the number of event boundaries from one to two increased the memory benefit. Clinical, imagistic and histopathological study of chronic apical periodontitis.

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Centrosomes do not function in this instance through their ability to nucleate microtubules. Proposed telemedicine partnership raises conflict-of-interest concerns. The anterior eye is comprised of an avascular cornea surrounded by a dense periocular vascular network and therefore serves as an excellent model for angiogenesis. We have previously reported that visuospatial working memory performance and magnitude of activation in the right dorsolateral prefrontal cortex predict the rate of manual visuomotor adaptation.

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Information regarding the metabolism of xenobiotic chemicals plays a central role in regulatory risk assessments. Nano-anchors with single protein capacity produced with STED lithography. Increased Plasma cGMP in a Family With Autosomal Recessive Retinitis Pigmentosa Due to Homozygous Mutations in the PDE6A Gene. We used data from 1030 postmenopausal breast cancer survivors to examine the association between serum estradiol levels, body mass index (BMI), physical activity, and RAND-36-item Health Survey (SF-36) physical health.

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An intensive lung donor treatment protocol does not have negative influence on other grafts: a multicentre study. On the automaticity of semantic processing during task switching. Development and validation of two food portion photograph books to assess dietary intake among adults and children in Central Africa. Lipid abnormalities and lipid-based repair strategies in atopic dermatitis.

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These differences appear to reflect both ancient shifts during millions of years of primate evolution and more recent changes due to modern hygiene. Retrospective analysis was performed over a two-year period on patients who were admitted as outpatients and underwent CEA.

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Prospective study in 23 preterm infants born between 27 and 36 weeks of pregnancy with features of intrauterine and postnatal hypoxia. The cellular and molecular biology of keratins: beginning a new era. To investigate the risk factors for prostatic inflammation extent and infection in patients with benign prostatic hyperplasia (BPH) so as to manage prostatic inflammation more efficiently. Sputum samples were analyzed using fluorescence microscopy, solid culture and Xpert.

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Skin biopsies were taken and chest X-rays were done at 0, 12 and 48 weeks. An electrical impedance spectroscopic (EIS) study on transport characteristics of ion-exchange membrane systems. Ipsilateral Alteration of Resting State Activity Suggests That Cortical Dysfunction Contributes to the Pathogenesis of Cluster Headache. To assess the influence of cognitive, functional and behavioral factors, co-morbidities as well as caregiver characteristics on driving cessation in dementia patients. The patient received laparoscopic herniorrhaphy with fixing of polypropylene mesh on the preperitoneal layer and he was discharged on the third postoperative day.

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The results showed that H1975 cell motility was related to EGFR expression in the absence of EF stimulation, while in the presence of EF it was associated with PTEN expression. Postoperative cerebrospinal fluid (CSF) leakage after translabyrinthine tumor resection remains a problem.

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Effects of externally-through-internally-mixed soot inclusions within clouds and precipitation on global climate. The work ability index is widely used in occupational health care.

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The mass was treated by unroofing, but a follow-up colonoscopy 5 days later revealed residual lipoma. The association between changes in height and obesity in Chilean preschool children: 1996-2004. Consistent with these observations, we found that six IFT proteins accumulate in the cilia of dyf-5(lf) mutants. A new procedure for the isolation of anti-HIV compounds (polysaccharides and polyphenols) from the marine alga Fucus vesiculosus.

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Genotoxic effect of copper on salivary gland polytene chromosomes of Chironomus riparius Meigen 1804 (Diptera, Chironomidae). Hegu (LI 4) led to the formation of a new thermal area in the lips. These surface-exposed syringe-like structures are highly conserved, necessary for pathogenesis, and hence are therapeutic targets against a number of Gram-negative pathogens. Six datasets were recorded, three corresponding to fatty cases and three containing synthetic dense tissue structures. Voxelwise analysis of the DTI data was performed by using TBSS to assess the relationship among FA, AD, and RD at TEA, and cognitive, fine-motor, and gross-motor scores at 2-year corrected age.

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Excess lifetime cancer risks are 14.4-18.1, 0.4-0.5, and 1.8-2.3 per 100,000 for all solid cancers combined, thyroid cancer, and leukemia, respectively. Numerous in vitro studies have evaluated the influence of opioids on many biological and immunological processes. This case illustrates the feasibility of transradial intervention for symptomatic coronary-cameral fistula. Benefits of Physical Exercise for Individuals with Fragile X Syndrome in Humans. Persistent infected wounds were observed only in full-thickness wounds covered with gauze.

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Binary and ternary intermetallic alloy systems are of interest for a variety of academic and technological applications. In this report, we describe a 6-year-old patient with the myeloradicular form of neuroschistosomiasis. Thus, the existence of bi-directional Delta-Notch signaling has been proposed.

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Modified content analysis methods were used to analyze the data and extract typologies of injecting drug users in Tehran. Most onsets of AD were in young adulthood, whereas MD had a flatter distribution across age. A self-assembly peptide nanofibrous scaffold reduces inflammatory response and promotes functional recovery in a mouse model of intracerebral hemorrhage. Considering the high agreement of HPV-DNA detection in PT and simultaneous HPV-DNA demonstration in the draining NM corroborating the monoclonal character of the tumour cells, the HPV-DNA presence in LN seems to be indicative of micro-metastasis in these lymph nodes.